The role of taxanes in triple-negative breast cancer: literature review.
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ABSTRACT:
SUBMITTER: Mustacchi G
PROVIDER: S-EPMC4532347 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
The role of taxanes in triple-negative breast cancer: literature review.
Mustacchi Giorgio G De Laurentiis Michelino M
Drug design, development and therapy 20150805
Breast cancer (BC) is the most frequent tumor worldwide. Triple-negative BCs are characterized by the negative estrogen and progesterone receptors and negative HER2, and represent 15% of all BCs. In this review, data on the use of taxanes in triple-negative BCs are analyzed, concluding they are effective in any clinical setting (neoadjuvant, adjuvant, and metastatic). Further, the role of nab-paclitaxel (formulation of albumin-bound paclitaxel) in these tumors is also evaluated. The available da ...[more]
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