Ontology highlight
ABSTRACT:
SUBMITTER: Marsay L
PROVIDER: S-EPMC4535279 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Marsay L L Dold C C Green C A CA Rollier C S CS Norheim G G Sadarangani M M Shanyinde M M Brehony C C Thompson A J AJ Sanders H H Chan H H Haworth K K Derrick J P JP Feavers I M IM Maiden M C MC Pollard A J AJ
The Journal of infection 20150515 3
<h4>Objectives</h4>Outer membrane vesicle (OMV) vaccines are used against outbreaks of capsular group B Neisseria meningitidis (MenB) caused by strains expressing particular PorA outer membrane proteins (OMPs). Ferric enterobactin receptor (FetA) is another variable OMP that induces type-specific bactericidal antibodies, and the combination of judiciously chosen PorA and FetA variants in vaccine formulations is a potential approach to broaden protection of such vaccines.<h4>Methods</h4>The OMV v ...[more]