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A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli.


ABSTRACT: Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an impact identifying ETEC isolates based on molecular screening of these biomarkers. We describe a novel coli surface antigen (CS) 8 subtype B (CS8B), a family of CFA/III pilus, in a toxin producing ETEC isolate from a Kenyan collection. In highlighting the existence of this putative CS, we provide the sequence and specific primers, which can be used alongside other ETEC primers previously described.

SUBMITTER: Njoroge SM 

PROVIDER: S-EPMC4535451 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli.

Njoroge Samuel M SM   Boinett Christine J CJ   Madé Laure F LF   Ouko Tom T TT   Fèvre Eric M EM   Thomson Nicholas R NR   Kariuki Samuel S  

Pathogens and disease 20150717 7


Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an impact identifying ETEC isolates based on molecular screening of these biomarkers. We describe a novel coli surface antigen (CS) 8 subtype B (CS8B), a family of CFA/III pilus, in a toxin producing ETEC i  ...[more]

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