Genome-wide gene expression profiling of acute metal exposures in male zebrafish.
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ABSTRACT:
SUBMITTER: Baer CE
PROVIDER: S-EPMC4535742 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Publications
Genome-wide gene expression profiling of acute metal exposures in male zebrafish.
Baer Christine E CE Ippolito Danielle L DL Hussainzada Naissan N Lewis John A JA Jackson David A DA Stallings Jonathan D JD
Genomics data 20141023
To capture global responses to metal poisoning and mechanistic insights into metal toxicity, gene expression changes were evaluated in whole adult male zebrafish following acute 24 h high dose exposure to three metals with known human health risks. Male adult zebrafish were exposed to nickel chloride, cobalt chloride or sodium dichromate at concentrations corresponding to their respective 96 h LC20, LC40 and LC60 (i.e. 96 h concentrations at which 20%, 40% and 60% lethality is expected, respecti ...[more]
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