Ontology highlight
ABSTRACT:
SUBMITTER: Ishibashi O
PROVIDER: S-EPMC4535841 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Genomics data 20140316
The periodontal ligament (PDL), connective tissue located between the cementum of teeth and alveolar bone of the mandibula, plays a crucial role in the maintenance and regeneration of periodontal tissues. We previously reported that endoglin was involved in the bone morphogenetic protein (BMP)-2-induced osteogenic differentiation of mouse PDL cells, which is associated with Smad-2 phosphorylation but not Smad-1/5/8 phosphorylation. Further, we found that the BMP-2-induced Smad-2 phosphorylation ...[more]