Transcriptional profiling of apoptosis-deficient Drosophila mutants.
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ABSTRACT:
SUBMITTER: Obata F
PROVIDER: S-EPMC4535892 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Publications
Transcriptional profiling of apoptosis-deficient Drosophila mutants.
Obata Fumiaki F Tomioka Katsura K Miura Masayuki M
Genomics data 20140810
Apoptosis is a fundamental way to remove damaged or unwanted cells during both developmental and post-developmental stages. Apoptosis deficiency leads to various diseases including cancer. To know the physiological changes in apoptosis-deficient mutants, we conducted non-biased transcriptomic analysis of Drosophila dark(cd4) mutants. As recently reported, combined with metabolome and genetic analysis, we identified systemic immune response, energy wasting, as well as alteration in S-adenosyl-met ...[more]
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