Transcriptomic profiling of trichloroethylene exposure in male mouse liver.
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ABSTRACT:
SUBMITTER: Jiang Y
PROVIDER: S-EPMC4535943 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
Transcriptomic profiling of trichloroethylene exposure in male mouse liver.
Jiang Yan Y Chen Jiahong J Tong Jian J Chen Tao T
Genomics data 20150115
Chronic Trichloroethylene (TCE) exposure could induce hepatocellular carcinoma in mice, and occupational exposure in humans was suggested to be associated with liver cancer. To understand the role of non-genotoxic mechanism(s) for TCE action, we examined the gene expression and DNA methylation changes in the liver of B6C3F1 mice orally administered with TCE for 5 days. As a beginning step, we profiled gene expression alterations induced by the TCE in mouse livers. Here we describe in detail the ...[more]
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