Ontology highlight
ABSTRACT:
SUBMITTER: Vieira FQ
PROVIDER: S-EPMC4537039 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Vieira Filipa Quintela FQ Costa-Pinheiro Pedro P Almeida-Rios Diogo D Graça Inês I Monteiro-Reis Sara S Simões-Sousa Susana S Carneiro Isa I Sousa Elsa Joana EJ Godinho Maria Inês MI Baltazar Fátima F Henrique Rui R Jerónimo Carmen C
Oncotarget 20150501 15
Prostate cancer (PCa) is one of the most incident cancers worldwide but clinical and pathological parameters have limited ability to discriminate between clinically significant and indolent PCa. Altered expression of histone methyltransferases and histone methylation patterns are involved in prostate carcinogenesis. SMYD3 transcript levels have prognostic value and discriminate among PCa with different clinical aggressiveness, so we decided to investigate its putative oncogenic role on PCa.We si ...[more]