Conducting polymer nanoparticles decorated with collagen mimetic peptides for collagen targeting.

ABSTRACT: We report on the formation of conducting polymer nanoparticles (CPNs), stabilized by a collagen mimetic peptide (CMP)-polymer amphiphile. CPNs ranging from ?15 to 40 nm were readily accessible upon modifying the amphiphile concentration. Surface presentation of CMPs on CPN precluded intra-/inter-particle trimerization, while preserving their ability to target collagen without pre-activation.

SUBMITTER: Santos JL 

PROVIDER: S-EPMC4537181 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature