Ontology highlight
ABSTRACT:
SUBMITTER: Budambula V
PROVIDER: S-EPMC4537595 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
AIDS research and therapy 20150815
<h4>Background</h4>Although injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations and their association with viral load and CD4+ T cell counts in HIV-1 infected IDUs (ART-naive, n = 32; and -experienced, n = 47) and non-drug users (ART-naive, n = 21; and -experienced, n = 32) naive for PI treatment from coastal Kenya.<h4>Results</h4>Only IDUs harboured ...[more]