Ontology highlight
ABSTRACT:
SUBMITTER: Goodwin CR
PROVIDER: S-EPMC4537791 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Goodwin Cody R CR Covington Brett C BC Derewacz Dagmara K DK McNees C Ruth CR Wikswo John P JP McLean John A JA Bachmann Brian O BO
Chemistry & biology 20150430 5
Secondary metabolite biosynthesis in microorganisms responds to discrete chemical and biological stimuli; however, untargeted identification of these responses presents a significant challenge. Herein we apply multiplexed stimuli to Streptomyces coelicolor and collect the resulting response metabolomes via ion mobility-mass spectrometric analysis. Self-organizing map (SOM) analytics adapted for metabolomic data demonstrate efficient characterization of the subsets of primary and secondary metabo ...[more]