Ontology highlight
ABSTRACT:
SUBMITTER: Kong A
PROVIDER: S-EPMC4540081 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Nature genetics 20080901 9
Uncertainty about the phase of strings of SNPs creates complications in genetic analysis, although methods have been developed for phasing population-based samples. However, these methods can only phase a small number of SNPs effectively and become unreliable when applied to SNPs spanning many linkage disequilibrium (LD) blocks. Here we show how to phase more than 1,000 SNPs simultaneously for a large fraction of the 35,528 Icelanders genotyped by Illumina chips. Moreover, haplotypes that are id ...[more]