Ontology highlight
ABSTRACT:
SUBMITTER: Yu G
PROVIDER: S-EPMC4541322 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Yu Guanghui G Xiang Hai H Tian Jianhui J Yin Jingdong J Pinkert Carl A CA Li Qiuyan Q Zhao Xingbo X
Scientific reports 20150819
In farm animals, mitochondrial DNA mutations exist widely across breeds and individuals. In order to identify differences among mtDNA haplotypes, two porcine transmitochondrial cybrids were generated by fusion of a Lantang pig cell line devoid of mitochondrial DNA with enucleated cytoplasm from either a Large White pig or a Xiang pig harboring potentially divergent mitochondrial haplotypes. These cybrid cells were subjected to mitochondrial genome sequencing, copy number detecting and analysis o ...[more]