Structural Characterization of Neutral Glycosphingolipids from 3T3-L1 Adipocytes.
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ABSTRACT:
SUBMITTER: Kojima H
PROVIDER: S-EPMC4541715 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
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Structural Characterization of Neutral Glycosphingolipids from 3T3-L1 Adipocytes.
Kojima Hisao H Suzuki Yusuke Y Ito Masahiro M Kabayama Kazuya K
Lipids 20150528 9
In recent years, obesity has been considered a pathological stage of early lifestyle-related diseases, and adipose tissue and adipocyte research has been active. Glycosphingolipids are involved in the pathogenesis of type 2 diabetes induced by insulin resistance, but the details of the glycosphingolipid molecular species composition of adipocytes have yet to be elucidated. We used 3T3-L1 adipocytes and the 1,2-dichloroethane-wash method to remove triacylglycerols, which are abundant in adipocyte ...[more]
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