Ontology highlight
ABSTRACT:
SUBMITTER: Serwa RA
PROVIDER: S-EPMC4543063 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Serwa Remigiusz A RA Abaitua Fernando F Krause Eberhard E Tate Edward W EW O'Hare Peter P
Chemistry & biology 20150806 8
Protein fatty acylation regulates diverse aspects of cellular function and organization and plays a key role in host immune responses to infection. Acylation also modulates the function and localization of virus-encoded proteins. Here, we employ chemical proteomics tools, bio-orthogonal probes, and capture reagents to study myristoylation and palmitoylation during infection with herpes simplex virus (HSV). Using in-gel fluorescence imaging and quantitative mass spectrometry, we demonstrate a gen ...[more]