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Metabolic syndrome across Europe: different clusters of risk factors.


ABSTRACT: BACKGROUND:Metabolic syndrome (MetS) remains a controversial entity. Specific clusters of MetS components - rather than MetS per se - are associated with accelerated arterial ageing and with cardiovascular (CV) events. To investigate whether the distribution of clusters of MetS components differed cross-culturally, we studied 34,821 subjects from 12 cohorts from 10 European countries and one cohort from the USA in the MARE (Metabolic syndrome and Arteries REsearch) Consortium. METHODS:In accordance with the ATP III criteria, MetS was defined as an alteration three or more of the following five components: elevated glucose (G), fasting glucose ?110?mg/dl; low HDL cholesterol, 102?cm for men or >88?cm for women. RESULTS:MetS had a 24.3% prevalence (8468 subjects: 23.9% in men vs. 24.6% in women, p?

SUBMITTER: Scuteri A 

PROVIDER: S-EPMC4544872 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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<h4>Background</h4>Metabolic syndrome (MetS) remains a controversial entity. Specific clusters of MetS components - rather than MetS per se - are associated with accelerated arterial ageing and with cardiovascular (CV) events. To investigate whether the distribution of clusters of MetS components differed cross-culturally, we studied 34,821 subjects from 12 cohorts from 10 European countries and one cohort from the USA in the MARE (Metabolic syndrome and Arteries REsearch) Consortium.<h4>Methods  ...[more]

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