Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC4546299 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Wang Ying Y Wu Kaichun K Yang Zhiping Z Zhao Qingchuan Q Fan Dongmei D Xu Po P Nie Yongzhan Y Fan Daiming D
PloS one 20150820 8
The effect of chemotherapy of gastric cancer (GC) remains very poor because of multidrug resistance (MDR). However, the mechanisms underlying MDR of GC remains far from fully understood. The aim of this study is to illustrate the potential mechanisms of the MDR of GC at mainly the long non-coding RNA (lncRNA) level. In this study, GC cell line, SGC7901, and two MDR sublines, SGC7901/VCR and SGC7901/ADR were subjected to an lncRNA microarray analysis. Bioinformatics and verification experiments w ...[more]