MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer.
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ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC4546440 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer.
Li Zheng Z Yu Xin X Shen Jianxiong J Law Priscilla T Y PT Chan Matthew T V MT Wu William K K WK
Oncotarget 20150601 16
Gallbladder cancer is the most common biliary tract malignancy with poor prognosis. MicroRNAs (miRNAs) are a class of small, endogenous, non-coding RNAs of 19-23 nucleotides in length, which regulate gene expression at post-transcriptional and translational levels. Several studies have demonstrated aberrant expression of miRNAs in gallbladder cancer tissues. Recent evidences also demonstrated that specific miRNAs are functionally involved in gallbladder cancer development through modulating cell ...[more]
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