In Vitro Fertilization in Women With Inflammatory Bowel Disease Is as Successful as in Women From the General Infertility Population.

ABSTRACT:

Background & aims

Inflammatory bowel disease (IBD) affects women of reproductive age, so there are concerns about its effects on fertility. We investigated the success of in vitro fertilization (IVF) in patients with IBD compared with the general (non-IBD) IVF population.

Methods

We conducted a matched retrospective cohort study of female patients with IBD who underwent IVF from 1998 through 2011 at 2 tertiary care centers. Patients were matched 4:1 to those without IBD (controls). The primary outcome was the cumulative rate of live births after up to 6 cycles of IVF. Secondary outcomes included the proportion of patients who became pregnant and the rate of live births for each cycle.

Results

Forty-nine patients with Crohn's disease (CD), 71 patients with ulcerative c

SUBMITTER: Oza SS 

PROVIDER: S-EPMC4546886 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature