Variation in the nuclear effects of infection by different human rhinovirus serotypes.
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ABSTRACT:
SUBMITTER: Walker EJ
PROVIDER: S-EPMC4547043 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Variation in the nuclear effects of infection by different human rhinovirus serotypes.
Walker Erin J EJ Jensen Lora M LM Croft Sarah S Ghildyal Reena R
Frontiers in microbiology 20150824
Human rhinovirus (HRV) is a positive sense RNA virus, which, despite replicating in the cytoplasm, has a significant impact on nuclear transport and nuclear localization of host proteins. A number of studies have identified differences between HRV serotypes, with respect to host response, protease activity and replicative ability. Here we report the sero-specific effects of two group-A HRV serotypes, the minor group HRV2 and the major group HRV16, on nuclear transport and nuclear protein localiz ...[more]
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