Ontology highlight
ABSTRACT:
SUBMITTER: Masson EA
PROVIDER: S-EPMC4548786 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Masson Elodie A Y EA Sibille Estelle E Martine Lucy L Chaux-Picquet Fanny F Bretillon Lionel L Berdeaux Olivier O
Journal of lipid research 20150704 9
Gangliosides (GGs) make a wide family of glycosphingolipids ubiquitously expressed in mammalian tissues and particularly abundant in the brain and nervous system. They exhibit a huge diversity due to structural variations in both their oligosaccharidic chain and ceramide moiety, which represent a real analytical challenge. Since their discovery in the 1940s, methods have persistently improved until the emergence of LC/MS, which offers a high level of specificity and sensitivity and is suitable w ...[more]