Chromatin states and nuclear organization in development--a view from the nuclear lamina.
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ABSTRACT:
SUBMITTER: Mattout A
PROVIDER: S-EPMC4549078 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Chromatin states and nuclear organization in development--a view from the nuclear lamina.
Mattout Anna A Cabianca Daphne S DS Gasser Susan M SM
Genome biology 20150825
The spatial distribution of chromatin domains in interphase nuclei changes dramatically during development in multicellular organisms. A crucial question is whether nuclear organization is a cause or a result of differentiation. Genetic perturbation of lamina-heterochromatin interactions is helping to reveal the cross-talk between chromatin states and nuclear organization. ...[more]
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