Ontology highlight
ABSTRACT:
SUBMITTER: Lee M
PROVIDER: S-EPMC4549759 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Lee Minjong M Yoon Jung-Hwan JH
World journal of biological chemistry 20150801 3
Aerobic glycolysis, i.e., the Warburg effect, may contribute to the aggressive phenotype of hepatocellular carcinoma. However, increasing evidence highlights the limitations of the Warburg effect, such as high mitochondrial respiration and low glycolysis rates in cancer cells. To explain such contradictory phenomena with regard to the Warburg effect, a metabolic interplay between glycolytic and oxidative cells was proposed, i.e., the "reverse Warburg effect". Aerobic glycolysis may also occur in ...[more]