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Consensus statement from the 2014 International Microdialysis Forum.


ABSTRACT: Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications.

SUBMITTER: Hutchinson PJ 

PROVIDER: S-EPMC4550654 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Consensus statement from the 2014 International Microdialysis Forum.

Hutchinson Peter J PJ   Jalloh Ibrahim I   Helmy Adel A   Carpenter Keri L H KL   Rostami Elham E   Bellander Bo-Michael BM   Boutelle Martyn G MG   Chen Jeff W JW   Claassen Jan J   Dahyot-Fizelier Claire C   Enblad Per P   Gallagher Clare N CN   Helbok Raimund R   Hillered Lars L   Le Roux Peter D PD   Magnoni Sandra S   Mangat Halinder S HS   Menon David K DK   Nordström Carl-Henrik CH   O'Phelan Kristine H KH   Oddo Mauro M   Perez Barcena Jon J   Robertson Claudia C   Ronne-Engström Elisabeth E   Sahuquillo Juan J   Smith Martin M   Stocchetti Nino N   Belli Antonio A   Carpenter T Adrian TA   Coles Jonathan P JP   Czosnyka Marek M   Dizdar Nil N   Goodman J Clay JC   Gupta Arun K AK   Nielsen Troels H TH   Marklund Niklas N   Montcriol Ambroise A   O'Connell Mark T MT   Poca Maria A MA   Sarrafzadeh Asita A   Shannon Richard J RJ   Skjøth-Rasmussen Jane J   Smielewski Peter P   Stover John F JF   Timofeev Ivan I   Vespa Paul P   Zavala Elizabeth E   Ungerstedt Urban U  

Intensive care medicine 20150901 9


Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on  ...[more]

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