Ontology highlight
ABSTRACT:
SUBMITTER: Olspert A
PROVIDER: S-EPMC4552492 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Olspert Allan A Chung Betty Y-W BY Atkins John F JF Carr John P JP Firth Andrew E AE
EMBO reports 20150625 8
The family Potyviridae encompasses ~30% of plant viruses and is responsible for significant economic losses worldwide. Recently, a small overlapping coding sequence, termed pipo, was found to be conserved in the genomes of all potyvirids. PIPO is expressed as part of a frameshift protein, P3N-PIPO, which is essential for virus cell-to-cell movement. However, the frameshift expression mechanism has hitherto remained unknown. Here, we demonstrate that transcriptional slippage, specific to the vira ...[more]