Ontology highlight
ABSTRACT:
SUBMITTER: Graber TG
PROVIDER: S-EPMC4553716 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
The journals of gerontology. Series A, Biological sciences and medical sciences 20140930 9
Frailty is a major cause of disability and loss of independence in the elderly. Using clinically relevant criteria from our previously established mouse frailty index, we investigated the effects of aerobic exercise on frailty in male C57BL/6 mice. In order to measure the effect of treatment on the individual animals, we constructed a composite score, the Frailty Intervention Assessment Value. We hypothesized voluntary aerobic exercise would improve individual criteria and reverse or prevent fra ...[more]