Ontology highlight
ABSTRACT:
SUBMITTER: Dong G
PROVIDER: S-EPMC4554922 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Open biology 20150801 8
Centrioles are short microtubule-based organelles with a conserved ninefold symmetry. They are essential for both centrosome formation and cilium biogenesis in most eukaryotes. A core set of five centriolar proteins has been identified and their sequential recruitment to procentrioles has been established. However, structures at atomic resolution for most of the centriolar components were scarce, and the underlying molecular mechanisms for centriole assembly had been a mystery--until recently. I ...[more]