Combined neurothrombectomy or thrombolysis with adjunctive delivery of 3K3A-activated protein C in acute ischemic stroke.
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ABSTRACT:
SUBMITTER: Amar AP
PROVIDER: S-EPMC4556986 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Combined neurothrombectomy or thrombolysis with adjunctive delivery of 3K3A-activated protein C in acute ischemic stroke.
Amar Arun Paul AP Griffin John H JH Zlokovic Berislav V BV
Frontiers in cellular neuroscience 20150902
In the treatment of acute ischemic stroke (AIS), vessel recanalization correlates with improved functional status and reduced mortality. Mechanical neurothrombectomy achieves a higher likelihood of revascularization than intravenous thrombolysis (IVT), but there remains significant discrepancy between rates of recanalization and rates of favorable outcome. The poor neurological recovery among some stroke patients despite successful recanalization confirms the need for adjuvant therapy, such as p ...[more]
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