Ontology highlight
ABSTRACT:
SUBMITTER: Komatsu T
PROVIDER: S-EPMC4557953 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Komatsu Tetsuro T Dacheux Denis D Kreppel Florian F Nagata Kyosuke K Wodrich Harald H
PloS one 20150902 9
Inside the adenovirus virion, the genome forms a chromatin-like structure with viral basic core proteins. Core protein VII is the major DNA binding protein and was shown to remain associated with viral genomes upon virus entry even after nuclear delivery. It has been suggested that protein VII plays a regulatory role in viral gene expression and is a functional component of viral chromatin complexes in host cells. As such, protein VII could be used as a maker to track adenoviral chromatin comple ...[more]