Ontology highlight
ABSTRACT:
SUBMITTER: Huang N
PROVIDER: S-EPMC4558147 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Huang Na N Wu Zhenzhen Z Lin Li L Zhou Minyu M Wang Lin L Ma Huanrong H Xia Jianling J Bin Jianping J Liao Yulin Y Liao Wangjun W
Oncotarget 20150601 17
MicroRNAs (miRNAs) are involved in the epithelial-mesenchymal transition (EMT) process and are associated with metastasis in gastric cancer (GC). MiR-338-3p has been reported to be aberrantly expressed in GC. In the present study, we show that miR-338-3p inhibited the migration and invasion of GC cells in vitro. Knocking down miR-338-3p in GC cells led to mesenchymal-like changes. MiR-338-3p influenced the expression of the EMT-associated proteins by upregulating the epithelial marker E-cadherin ...[more]