Ontology highlight
ABSTRACT:
SUBMITTER: Tan X
PROVIDER: S-EPMC4558397 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Integrative biology : quantitative biosciences from nano to macro 20150724 9
Clathrin-mediated endocytosis (CME) is the most characterized pathway for the endocytic entry of proteins and lipids at the plasma membrane of eukaryotic cells. Numerous studies have probed the roles of different endocytic accessory proteins in regulating the dynamics of clathrin-coated pit (CCP) assembly. However, it is not completely clear how physical cues regulate CCP dynamics. Here we employ microcontact printing to control cell shape and examine CCP dynamics as a function of cell spreading ...[more]