Ontology highlight
ABSTRACT:
SUBMITTER: Migliaccio R
PROVIDER: S-EPMC4559486 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Migliaccio Raffaella R Agosta Federica F Possin Katherine L KL Canu Elisa E Filippi Massimo M Rabinovici Gil D GD Rosen Howard J HJ Miller Bruce L BL Gorno-Tempini Maria Luisa ML
Journal of Alzheimer's disease : JAD 20150101 2
The term early-onset Alzheimer's disease (EOAD) identifies patients who meet criteria for AD, but show onset of symptoms before the age of 65. We map progression of gray matter atrophy in EOAD patients compared to late-onset AD (LOAD). T1-weighted MRI scans were obtained at diagnosis and one-year follow-up from 15 EOAD, 10 LOAD, and 38 age-matched controls. Voxel-based and tensor-based morphometry were used, respectively, to assess the baseline and progression of atrophy. At baseline, EOAD patie ...[more]