Ontology highlight
ABSTRACT:
SUBMITTER: Matsson P
PROVIDER: S-EPMC4559557 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Matsson Pär P Bergström Christel A S CA
In silico pharmacology 20150904 1
Transport proteins are important mediators of cellular drug influx and efflux and play crucial roles in drug distribution, disposition and clearance. Drug-drug interactions have increasingly been found to occur at the transporter level and, hence, computational tools for studying drug-transporter interactions have gained in interest. In this short review, we present the most important transport proteins for drug influx and efflux. Computational tools for predicting and understanding the substrat ...[more]