The effect of immediate breast reconstruction on the timing of adjuvant chemotherapy: a systematic review.

ABSTRACT: Adjuvant chemotherapy is often needed to achieve adequate breast cancer control. The increasing popularity of immediate breast reconstruction (IBR) raises concerns that this procedure may delay the time to adjuvant chemotherapy (TTC), which may negatively impact oncological outcome. The current systematic review aims to investigate this effect. During October 2014, a systematic search for clinical studies was performed in six databases with keywords related to breast reconstruction and chemotherapy. Eligible studies met the following inclusion criteria: (1) research population consisted of women receiving therapeutic mastectomy, (2) comparison of IBR with mastectomy only groups, (3) TTC was clearly presented and mentioned as outcome measure, and (4) original studies only (e.g., cohort stud

SUBMITTER: Xavier Harmeling J 

PROVIDER: S-EPMC4559567 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature