Update of sleep alterations in depression.
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ABSTRACT:
SUBMITTER: Medina AB
PROVIDER: S-EPMC4559588 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
Update of sleep alterations in depression.
Medina Andrés Barrera AB Lechuga DeboraYoaly Arana DA Escandón Oscar Sánchez OS Moctezuma Javier Velázquez JV
Sleep science (Sao Paulo, Brazil) 20140927 3
Sleep disturbances in depression are up to 70%. Patients frequently have difficulty in falling asleep, frequent awakenings during the night and non-restorative sleep. Sleep abnormalities in depression are mainly characterized by increased rapid eye movement (REM) sleep and reduced slow wave sleep. Among the mechanisms of sleep disturbances in depression are hyperactivation of the hypothalamic-pituitary-adrenal axis, CLOCK gene polymorphism and primary sleep disorders. The habenula is a structure ...[more]
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