Ontology highlight
ABSTRACT:
SUBMITTER: Cavaliere P
PROVIDER: S-EPMC4559669 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Cavaliere Paola P Sizun Christina C Levi-Acobas Fabienne F Nowakowski Mireille M Monteil Véronique V Bontems François F Bellalou Jacques J Mayer Claudine C Norel Françoise F
Scientific reports 20150904
In many Gram-negative bacteria, including Salmonella enterica serovar Typhimurium (S. Typhimurium), the sigma factor RpoS/σ(S) accumulates during stationary phase of growth, and associates with the core RNA polymerase enzyme (E) to promote transcription initiation of genes involved in general stress resistance and starvation survival. Whereas σ factors are usually inactivated upon interaction with anti-σ proteins, σ(S) binding to the Crl protein increases σ(S) activity by favouring its associati ...[more]