Ontology highlight
ABSTRACT:
SUBMITTER: Fu Y
PROVIDER: S-EPMC4559819 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Fu Yanbin Y Huang Chenwen C Huang Chenwen C Xu Xinxiu X Gu Haifeng H Ye Youqiong Y Jiang Cizhong C Qiu Zilong Z Xie Xin X
Cell research 20150821 9
The direct conversion, or transdifferentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provides promising approaches for cardiac regeneration. However, genetic manipulations raise safety concerns and are thus not desirable in most clinical applications. The discovery of full chemically induced pluripotent stem cells suggest the possibility of replacing transcription factors with chemical cocktails. Here, we report the generation of au ...[more]