Ontology highlight
ABSTRACT:
SUBMITTER: Sterling TR
PROVIDER: S-EPMC4560029 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Sterling Timothy R TR Moro Ruth N RN Borisov Andrey S AS Phillips Elizabeth E Shepherd Gillian G Adkinson Newton Franklin NF Weis Stephen S Ho Christine C Villarino Margarita Elsa ME
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20150422 4
<h4>Background</h4>Weekly rifapentine plus isoniazid for 3 months (3HP) is as effective as daily isoniazid for 9 months (9H) for latent tuberculosis infection in high-risk persons, but there have been reports of possible flu-like syndrome.<h4>Methods</h4>We identified clinically significant systemic drug reactions (SDR) and evaluated risk factors in patients who did not complete treatment in the PREVENT Tuberculosis study.<h4>Results</h4>Among 7552 persons who received ≥ 1 dose of study drug, 15 ...[more]