Ontology highlight
ABSTRACT:
SUBMITTER: Daniels BC
PROVIDER: S-EPMC4560822 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Daniels Bryan C BC Nemenman Ilya I
Nature communications 20150821
Dynamics of complex systems is often driven by large and intricate networks of microscopic interactions, whose sheer size obfuscates understanding. With limited experimental data, many parameters of such dynamics are unknown, and thus detailed, mechanistic models risk overfitting and making faulty predictions. At the other extreme, simple ad hoc models often miss defining features of the underlying systems. Here we develop an approach that instead constructs phenomenological, coarse-grained mode ...[more]