Ontology highlight
ABSTRACT:
SUBMITTER: Huang YL
PROVIDER: S-EPMC4560832 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Huang Yen-Lin YL Chassard Christophe C Hausmann Martin M von Itzstein Mark M Hennet Thierry T
Nature communications 20150825
Rapid shifts in microbial composition frequently occur during intestinal inflammation, but the mechanisms underlying such changes remain elusive. Here we demonstrate that an increased caecal sialidase activity is critical in conferring a growth advantage for some bacteria including Escherichia coli (E. coli) during intestinal inflammation in mice. This sialidase activity originates among others from Bacteroides vulgatus, whose intestinal levels expand after dextran sulphate sodium administration ...[more]