Associations between early adrenarche, affective brain function and mental health in children.
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ABSTRACT:
SUBMITTER: Whittle S
PROVIDER: S-EPMC4560948 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
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Associations between early adrenarche, affective brain function and mental health in children.
Whittle Sarah S Simmons Julian G JG Byrne Michelle L ML Strikwerda-Brown Cherie C Kerestes Rebecca R Seal Marc L ML Olsson Craig A CA Dudgeon Paul P Mundy Lisa K LK Patton George C GC Allen Nicholas B NB
Social cognitive and affective neuroscience 20150211 9
Early timing of adrenarche, associated with relatively high levels of Dehydroepiandrosterone (DHEA) in children, has been associated with mental health and behavioral problems. However, little is known about effects of adreneracheal timing on brain function. The aim of this study was to investigate the effects of early adrenarche (defined by high DHEA levels independent of age) on affective brain function and symptoms of psychopathology in late childhood (N = 83, 43 females, M age 9.53 years, s. ...[more]
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