Ontology highlight
ABSTRACT:
SUBMITTER: Groenman AP
PROVIDER: S-EPMC4561224 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Groenman Annabeth P AP Greven Corina U CU van Donkelaar Marjolein M J MM Schellekens Arnt A van Hulzen Kimm J E KJ Rommelse Nanda N Hartman Catharina A CA Hoekstra Pieter J PJ Luman Marjolein M Franke Barbara B Faraone Stephen V SV Oosterlaan Jaap J Buitelaar Jan K JK
Addiction biology 20150306 4
Individuals with attention deficit/hyperactivity disorder (ADHD) are at increased risk of developing substance use disorders (SUDs) and nicotine dependence. The co-occurrence of ADHD and SUDs/nicotine dependence may in part be mediated by shared genetic liability. Several neurobiological pathways have been implicated in both ADHD and SUDs, including dopamine and serotonin pathways. We hypothesized that variations in dopamine and serotonin neurotransmission genes were involved in the genetic liab ...[more]