Identification and analysis of the N(6)-methyladenosine in the Saccharomyces cerevisiae transcriptome.
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ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC4561376 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Identification and analysis of the N(6)-methyladenosine in the Saccharomyces cerevisiae transcriptome.
Chen Wei W Tran Hong H Liang Zhiyong Z Lin Hao H Zhang Liqing L
Scientific reports 20150907
Knowledge of the distribution of N(6)-methyladenosine (m(6)A) is invaluable for understanding RNA biological functions. However, limitation in experimental methods impedes the progress towards the identification of m(6)A site. As a complement of experimental methods, a support vector machine based-method is proposed to identify m(6)A sites in Saccharomyces cerevisiae genome. In this model, RNA sequences are encoded by their nucleotide chemical property and accumulated nucleotide frequency inform ...[more]
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