Ontology highlight
ABSTRACT:
SUBMITTER: Kato K
PROVIDER: S-EPMC4564812 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kato Kentaro K Yahata Kazuhide K Gopal Dhoubhadel Bhim B Fujii Yoshito Y Tachibana Hiroshi H
Scientific reports 20150910
Galactose and N-acetyl-D-galactosamine (Gal/GalNAc) inhibitable lectin of Entamoeba histolytica, a common protozoan parasite, has roles in pathogenicity and induction of protective immunity in mouse models of amoebiasis. The lectin consists of heavy (Hgl), light (Lgl), and intermediate (Igl) subunits. Hgl has lectin activity and Lgl does not, but little is known about the activity of Igl. In this study, we assessed various regions of Igl for hemagglutinating activity using recombinant proteins e ...[more]