Ontology highlight
ABSTRACT:
SUBMITTER: Jin EH
PROVIDER: S-EPMC4565350 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Jin Eun-Heui EH Kim JaeWoo J Lee Sang-Il SI Hong Jang Hee JH
International journal of clinical and experimental medicine 20150715 7
The DNA repair system plays a pivotal role in maintaining genomic integrity and protection against mutations that could lead to cancer development. The aim of this study was to explore the association between common polymorphisms of DNA repair genes, APE1 (rs1760944 and rs1130409) and XRCC1 (rs1799782, rs25487, and rs25489), and gastric cancer (GC) risk in the Korean population. We conducted a case-control study of 368 GC patients and 398 controls by using TaqMan genotyping assay. None of the po ...[more]