Ontology highlight
ABSTRACT:
SUBMITTER: Komaba S
PROVIDER: S-EPMC4567078 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Komaba Shigeru S Coluccio Lynne M LM
PloS one 20150911 9
Amino acid transporters (AATers) in the brush border of the apical plasma membrane (APM) of renal proximal tubule (PT) cells mediate amino acid transport (AAT). We found that the membrane-associated class I myosin myosin 1b (Myo1b) localized at the apical brush border membrane of PTs. In opossum kidney (OK) 3B/2 epithelial cells, which are derived from PTs, expressed rat Myo1b-GFP colocalized in patched microvilli with expressed mouse V5-tagged SIT1 (SIT1-V5), which mediates neutral amino acid t ...[more]