Ontology highlight
ABSTRACT:
SUBMITTER: Alanazi M
PROVIDER: S-EPMC4567226 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Alanazi Mohammed M Alabdulkarim Huda A HA Shaik Jilani P JP Al Naeem Abdulrahman A Elrobh Mohammad M Al Amri Abdullah A Al-Mukaynizi Fatimah Basil FB Semlali Abdelhabib A Warsy Arjumand A Parine Narasimha Reddy NR
OncoTargets and therapy 20150903
<h4>Background</h4>Cytochrome P450 (CYP)19A1 encodes aromatase, the enzyme responsible for the conversion of androgens to estrogens, and may play a role in variation in outcomes among women with breast cancer. The aim of this study was to analyze the genetic association of rs4646 (A > C) and rs700518 (Val > Val) in the CYP19A1 gene with the risk of breast cancer.<h4>Methods</h4>These two single nucleotide polymorphisms (SNPs) were analyzed in a primary study group of breast cancer patients and h ...[more]