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Monoterpenoid Indole Alkaloids from Inadequately Dried Leaves of Alstonia scholaris.


ABSTRACT: Six new indole alkaloids, named alstoniascholarines L-Q (1-6), together with nineteen known analogues were isolated from the inadequately dried leaves of Alstonia scholaris. Their structures were elucidated on the basis of extensive analysis of spectroscopic data and by comparison of their physical and spectroscopic data with the literature values. In addition, the new alkaloids were tested for their cytotoxic and neurite outgrowth-promoting activities.

SUBMITTER: Qin XJ 

PROVIDER: S-EPMC4567994 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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Monoterpenoid Indole Alkaloids from Inadequately Dried Leaves of Alstonia scholaris.

Qin Xu-Jie XJ   Zhao Yun-Li YL   Song Chang-Wei CW   Wang Bei B   Chen Ying-Ying YY   Liu Lu L   Li Qiong Q   Li Dan D   Liu Ya-Ping YP   Luo Xiao-Dong XD  

Natural products and bioprospecting 20150818 4


Six new indole alkaloids, named alstoniascholarines L-Q (1-6), together with nineteen known analogues were isolated from the inadequately dried leaves of Alstonia scholaris. Their structures were elucidated on the basis of extensive analysis of spectroscopic data and by comparison of their physical and spectroscopic data with the literature values. In addition, the new alkaloids were tested for their cytotoxic and neurite outgrowth-promoting activities. ...[more]

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