Ontology highlight
ABSTRACT:
SUBMITTER: Huang CY
PROVIDER: S-EPMC4568463 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Huang Chao-Yuan CY Huang Shu-Pin SP Lin Victor C VC Yu Chia-Cheng CC Chang Ta-Yuan TY Lu Te-Ling TL Chiang Hung-Chih HC Bao Bo-Ying BY
Scientific reports 20150914
Autophagy is a complex process of autodigestion in conditions of cellular stress, and it might play an important role in the pathophysiology during carcinogenesis. We hypothesize that genetic variants of the autophagy pathway may influence clinical outcomes in prostate cancer patients. We genotyped 40 tagging single-nucleotide polymorphisms (SNPs) from 7 core autophagy pathway genes in 458 localized prostate cancer patients. Multivariate Cox regression was performed to evaluate the independent a ...[more]