Ontology highlight
ABSTRACT:
SUBMITTER: McMillan DJ
PROVIDER: S-EPMC4568957 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
McMillan D J DJ Drèze P-A PA Vu T T Vu T T Bessen D E DE Guglielmini J J Steer A C AC Carapetis J R JR Van Melderen L L Sriprakash K S KS Smeesters P R PR
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20130307 5
Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing). Although >200 emm-types are characterized, structural data were obtained from only a limited number of emm-types. We aim to evaluate the sequence diversity of near-full-length M proteins from worldwide sources and analyse their structure, sequence conservation and classification. GAS isolates recovered from throughout the world during the ...[more]